Accurate prediction of inter-protein residue-residue contacts for homo-dimeric protein complexes through deep leaning
The new version of DeepHomo,
DeepHomo2.0, is available now ! new
Download the DeepHomo package
Users may also want to download the
DeepHomo data sets and
DeepHomo test sets
to try the model on your own.
In addition, users may also want to cite:
Yumeng Yan, Sheng-You Huang,
Accurate prediction of inter-protein residue-residue contacts for homo-oligomeric protein complexes
Briefings in Bioinformatics, DOI: 10.1093/bib/bbab038, (in press).
Remmert M, Biegert A, Hauser A, Söding J. HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment. Nat Methods. 2011 Dec 25;9(2):173-5.
Seemayer S, Gruber M, Söding J. CCMpred--fast and precise prediction of protein residue-residue contacts
from correlated mutations. Bioinformatics. 2014;30(21):3128-30.
Kabsch W, Sander C. Dictionary of protein secondary structure:
pattern recognition of hydrogen-bonded and geometrical features.
Yan Y, Huang SY. CHDOCK:
a hierarchical docking approach for modeling Cn symmetric
homo-oligomeric complexes. Biophys. Rep. 2019;5(2):65-72.
Yan Y, Tao H, Huang SY. HSYMDOCK: a docking web server for
predicting the structure of protein homo-oligomers with Cn or Dn
symmetry. Nucleic Acids Res. 2018;46(W1):W423-W431.
Wang S, Sun S, Li Z, Zhang R, Xu J. Accurate De Novo Prediction of
Protein Contact Map by Ultra-Deep Learning Model. PLoS Comput
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